Olympus LV200 Inverted Microscope

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LV200 Inverted Microscope

Bioluminescence Imaging System

The LV200 has been carefully designed for long-duration cell bioluminescence. A completely new optical design dramatically increases sensitivity and enables the detailed study of photosensitive cells and luminescence probes at high magnification. The built-in system for temperature control, humidity and gas flow helps to keep the cultured cells or tissue slices in a healthy condition throughout the observation period and the unique light-tight enclosure shields the sample and optics from any external light.

Features

  • Cell-friendly Imaging
    Luminescence comes from within the sample and is in turn non-toxic to the cells. There is also no background noise or autofluorescence to worry about. Luminescence is, therefore, the right light for live cell imaging.
  • Overcoming the Limitations of Fluorescence
    Fluorescence microscope and related techniques have many advantages, but also a number of limitations. Bioluminescence imaging has the potential to overcome these limitations. The unique optical design of the new Olympus LV200 brings together the advantages of fluorescence and bioluminescence to create a system capable of acquiring bright, high- resolution images.
  • High-quality Images
    Olympus has developed the LV200 LUMINOVIEW bioluminescent imaging system, which provides amazingly detailed images using standard CCDs rather than specialized photon detectors. To do this, the optical design of the system is highly specialized to maximize light collection - an essential aspect, given the low levels of light emitted.
  • Use in Normal Lab Environment
    The light-tight enclosure of the LV200 shields the samples and optics from external light and allows the microscope to be used under ambient light in the laboratory. For applications or samples that require very long exposure times, the microscope might have to be moved to a low-light room.
  • Expanding Current Imaging Capabilities
    With optical components optimized for the detection of luminescent light, the LV200 is further designed to match the requirements of a broad range of research. It has integrated excitation and emission filter wheels to enable dual-color luminescence as well as transmitted light fluorescence imaging. With standard brightfield illumination and phase contrast inserts, target areas of the sample can be found easily before switching to luminescence detection. It is, therefore, also possible to produce luminescent and fluorescent overlays on brightfield images, which enables localization and colocalization capabilities that were not previously possible.