The Malvern MicroCal VP Capillary Differential Scanning Calorimeter (DSC) characterizes protein and biomolecule stability, and the resulting data is used to guide biopharmaceutical applications ranging from protein engineering to final product development. The DSC measures the intramolecular stability of macromolecules such as proteins and nucleic acids, or complexes such as oligomeric proteins and lipids. This is a high-throughput, high sensitivity DSC with low sample consumption.
This high-throughput DSC system includes powerful, easy to use software that helps to streamline your workflow by simplifying experiment setups and instrument scheduling. The software automates data analysis and sorting which helps to keep your workflow running smoothly and efficiently and reduces analysis time from days to hours.
Specifications:
| Active Cell Volume | 130µL |
| Typical Minimum Protein Concentrations | 0.2mg/ml |
| Maximum Scan Rate | 240°C/hr |
| Temperature Range | -10°C to 130°C |
| Typical Time per Scan | 35 to 55 minutes, depending on scan rate and temperature |
| Maximum Scans per Day | ~50 |
| Automated Cell Filling and Washing | Yes |
| Samples per 96 Well Plate | 48 |
| Measurement Parameter | Temperature midpoint Tm
Enthalpy ΔH Heat capacity change ΔCp |
| Cell Configuration | Capillary |
| Noise | 0.05 μCal/oC |
| Response time | 5 sec |
| Multiple Feedback modes | Yes (passive, high gain, low gain) |
| Baseline repeatability | 1.5 μCal/oC |
| Operating environment | 10 oC to 28 oC
0% to 70% RH, non condensing |
| Dimensions | 8x18x8” |
| Weight | 30 lbs |
| Electrical | 120V, 10A |
Includes:
- Malvern MicroCal VP Differential Scanning Calorimeter | CAT# VP-Cap DSC | MSRP: $78,241.33
- Computer Workstation Running Malvern Software
- Microcal ThermVac
- Microcal VP Capillary DSC
- LCD Monitor, Keyboard & Mouse
- Tubing
- Communication Cables
- User Manual
- 120V Power Cord (10A)
