Complete and refurbished GE AKTA™ Crossflow system, decontaminated and ready for operation which includes:
- Fully Refurbished System
- Preventative Maintenance prior to shipping
- Computer workstation pre-loaded with control software
- All power/communication cables and User Manual
- Performance Data from Testing showing the system functions within all OEM specifications
The ÄKTAcrossflow™ is a fully automated cross flow filtration system for process development and it is suitable for filter screening and process optimization at small-scale as well as small-scale processing.
- Broad range of applications that cover ultrafiltration and microfiltration.
- Flexible operation of either hollow fiber cartridges or cross flow cassettes.
- Thorough and efficient process development with full TMP and flux scouting.
- Single, familiar software interface for both chromatography and cross flow filtration.
- Minimum working volume of 25 mL ensures operation of complete processes using filters between 40 cm2 and 150 cm2.
- Suitable for small-scale processing where limited material is available.
The purification of biomolecules normally uses cross flow filtration to concentrate and wash feed prior to chromatography. The AKTA™ Crossflow is a fully automated system for cross flow filtration (ultrafiltration/diafiltration and cell separation) designed for process development and optimization.
The control software for this system has the benefits of one common control platform and user interface for all scales of operation in filtration and chromatography, and is compatible with all applicable regulations including 21 CFR Part 11. The scouting feature gives automatic support to process development and optimization. Method wizards and pre-programmed cleaning methods provide a high degree of efficiency in scale-up and production work.
The system can be used with flat sheet cassettes and hollow fibers. A wide range of cross flow devices include MidGee™ hollow fiber cross flow cartridges and Kvick Start™ flat sheet cassettes. The cassettes are available in 40 cm2 and 150 cm2 for ultrafiltration as well as diafiltration process development and require small working volume. The AKTA™ Crossflow comes complete with UV, pH and conductivity detectors as well as air, pressure and temperature sensors. The valves and the fittings are specially developed for hygienic, leak-free operation. Electrically actuated diaphragm valves diminish hold up volumes and prevent dead volumes.
